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UTERINE (ENDOMETRIAL) CANCER
Uterine (Endometrial) cancer originates in the female reproductive system and generally affects postmenopausal women between ages 50 and 60;. It develops in the body of the uterus or womb whose wall has an inner lining (called the endometrium) and an outer layer of muscle tissue (called the myometrium).
Endometrial cancer (Uterine Cancer) is often detected at an early stage because it frequently produces vaginal bleeding between menstrual periods or after menopause. If discovered early, this slow-growing cancer is likely to be confined to the uterus. Removing the uterus surgically (Hysterectomy) successfully eliminates endometrial cancer, if detected and carried out in the initial stages.
Dharamshila Hospital And Research Centre is one of the top cancer hospitals of India for advanced cancer treatment. Dharamshila Hospital offers comprehensive care for patients with Endometrial Cancer, including advanced diagnosis and best treatment options. The Department has been regularly carrying out extensive and radical surgeries for all gynecological cancers and achieving good results.
Such extensive surgeries usually require additional training and experience compared to general gynecology. In addition, management of cancer today follows a multimodality approach, and integration of surgery with non-surgical treatments such as, chemotherapy and radiation therapy is essential to improve outcome. Gynecological oncologists are best suited for this as they are focusing only on gynecological cancers.
To determine, if uterine cancer is present, Gyneconcologist at DHRC will see the medical history of the patient and conduct a physical examination. During a pelvic exam the Gyneconcologist will feel for lumps or abnormalities in the uterus of the patient.
Other diagnostic tests may include:
- Ultrasound or transvaginal ultrasound. In transvaginal ultrasound, Gyneconcologist inserts a wandlike device (transducer) into the vagina, which creates a video image of the uterus using sound waves.
- Endometrial biopsy. In a biopsy, Gyneconcologist removes cells from the lining of the uterus and examines them in a laboratory.
If Gyneconcologist finds cancer of the uterine lining (endometrium) or uterine sarcoma, she may recommend exploratory surgery to determine how far the cancer has progressed.
Surgery is the most common approach to treating uterine cancer. Additional therapy to destroy uterine cancer cells may include radiation, cancer-killing drugs (chemotherapy) and hormone therapy.
- Surgery. During exploratory surgery, oncopathologist, who specialize in tissue study examine the cancer tissue so that Gyneconcologist can determine how much tissue to remove. In most cases, Gyneconcologist will recommend a hysterectomy (removal of the uterus) or a complete hysterectomy (removal of the uterus, fallopian tubes and ovaries). To find out whether the cancer has spread, Gyneconcologist also removes tissue from the lymph nodes near the uterus and other abdominal sites.
- Radiation therapy. Radiation (high-level beams) kills microscopic cancer cells that may remain after surgery. If the patient have an aggressive form of uterine cancer or are at high risk for recurrence, she may need radiation after surgery. Occasionally, Gyneconcologist may recommend radiation instead of surgery, if the tumor can't be removed safely. She may receive external beam radiation or Brachytherapy. If she receives external radiation, Gyneconcologist may recommend Intensity Modulated Radiation Therapy (IMRT) or Image Guided Radiation Therapy (IGRT) to decrease damage to nearby healthy tissue.
Intensity Modulated Radiation Therapy (IMRT)
This highly complex and promising technique was started at Dharamshila Hospital in 2005. Now, IMRT is being delivered through VMAT techniques in a continuous arc around patient effectively, from infinite delivery angles; reducing the integral dose to one tenth and treatment time to few minutes. IMRT is used for tumours arising from
Head and Neck, Brain, Lungs, Lymphomas and Gyneccological Cancers.
Image Guided Rad7iation Therapy (IGRT)
IGRT has been evolved to enable clinicians to treat the tumours that move with internal motion. IGRT provides a very effective means for mitigating the risk of tumor motion. Real time image guidance and adaptive radiation therapy involves constantly imaging the motion of the tumour during treatment delivery and changing beam delivery on the fly to compensate for undesired motion. IGRT is most suitable for Tumours of the
Prostate, Urinary Bladder, Lungs and Gyneccological cancers.
- Hormone therapy. Gyneconcologist may recommend progestin (synthetic progesterone) to help stop the cancer from spreading. Patient may take progestin with other medications.
- Chemotherapy. In chemotherapy, drugs given by mouth or intravenously (through a vein) destroy cancer cells. Chemotherapy after removal of the tumor may improve treatment success if the patient has advanced endometrial cancer.
After the patient completed her treatment, Gyneconcologist will provide follow-up care that includes physical exams, pelvic exams, Pap smears, chest X-rays and laboratory tests.
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